Peyronies Plastic Surgury

AUXILIUM : Pharmaceuticals Announces Results from Three Year CORDLESS ...

"In my opinion, the recurrence rate seen with XIAFLEX is comparable with or better than other minimally-invasive treatment options. More importantly, the fingers I have treated with XIAFLEX do not appear to develop scar tissue, as opposed to surgically treated fingers. Scar slows recovery and complicates further treatment," said Dr. Tom Kaplan, of the Indiana Hand to Shoulder Center. "As a result, first-line use of XIAFLEX preserves all of my treatment options for those patients who do recur."

The study also tracks whether a joint successfully treated with XIAFLEX received any further medical intervention. Through year three of follow-up 93.1% of joints that were successfully treated with XIAFLEX did not receive any medical or surgical intervention. Of the 43 (6.9 %) successfully treated joints that received medical or surgical intervention through three years, 30 had surgery, seven received needle aponeurotomy (of which 2 subsequently received a third intervention), and six received XIAFLEX. XIAFLEX has been commercially available in the U.S. only since March 2010.

"While I am very impressed with the three year recurrence rate of 35% using a 20 degree change to define recurrence, the surgical literature has often defined recurrence as a 30 degree change. Using this definition, XIAFLEX demonstrates an even lower 22% recurrence rate at three years," said Dr. Vincent Hentz, Professor Emeritus, Surgery - Plastic/Recon Surgery, Stanford Medical School. "With this longer term data, I believe that treatment with XIAFLEX of Dupuytren's patients' palpable cords can provide durable outcomes with a very acceptable rate of recurrence in the majority of patients."

Although there is no standard methodology to measure recurrence, the literature(2,3,4), on surgical treatment does reference a definition of recurrence as a 30 degree worsening of contracture following an intervention.

Peyronies Disease and Its Treatment | Premature Ejaculation

Do you know Francois de la Peyronie? He is a well-known doctor during his time, the surgeon of King Louis XIV of France. Peyronie’s disease was named after him because he was the first man to discover this uncommon condition during 1973. Let’s know more about Peyronie’s disease.

Tunica Albuginea is the whitish membrane within the penis that surrounds the spongy chambers of Corpora Cavernosa. For reasons unknown to science at this moment, scar tissue begins to form in the Tunica Albuginea. This tissue prevents the normal expansion of the penis during erections and, in time, forms a permanent bend in the penis to one side or the other.

At first, the disease is painful but the pain eventually goes away on its own. You don’t need to resort to painkillers or to fear falling into the trap of long-term abuse of such pills. Curvature is the only effect of this disease. It is visible when the penis is erect, and possibly a shortening of the penis in the flaccid state. Most men suffering from it are able to have sex with their partners and experience no pain during intercourse. Nevertheless, as the angle of the curvature draws close to 90 degrees, intercourse becomes more and more of a problem.

The disease can affect men of all races and ages. It is most commonly seen in Caucasian males ages 40 and up. It is not contagious and is in no way related to cancer or other serious conditions. There is no known universal cure and some of the men which science was able to help have experienced relapses. The list of treatments developed to fight Peyronie’s disease is quite large, but not one of them was proved to be the best solution to the problem.

One of the most recommended treatments is surgery. Severe cases are always solved through the insertion of implants via surgical intervention. A couple of years ago, surgery were the method of choice for treating Peyronie’s disease because there were no proven alternatives.

• Penile implants – inlude plastic cylinders, either solid or inflatable, which are placed inside the Corpora Cavernosa. The surgeon can either place the implants inside the penis or let them do the work of straightening out the organ, or he can try to bend the penis against the plaque in order to increase the implant’s chance of successfully correcting the curvature.

• The use of tissue grafts – it is another widespread way of attempting to treat Peyronie’s disease. This procedure entails the complete surgical removal of the lump of plaque that develops on the penis and straightening the penis in order to bring it back to the original shape. Doctors tend to advise patients to accept this approach in cases featuring large plaques or severely bent penises.

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